105 Main Street
Syracuse, NY 13212 · Onondaga County
Price
$400,000
Bed / Bath
—
Interior
2,244 sqft
Lot
10,093 sqft lot
Built
1950
About this home
Well-maintained, single-story commercial building at 105 N Main Street in North Syracuse, NY. This 2,244 square foot medical office has been in continuous professional use for over 60 years and currently houses an established optometry practice operating at this location for 29 years. The building sits on a 0.23-acre lot with 15 dedicated parking spaces and offers high visibility on North Main Street. The property received a new roof in 2024, significantly reducing near-term capital expenditure risk for the buyer. The interior features a professionally designed layout with reception and optical retail areas, multiple fully equipped exam rooms, private offices, and a laboratory space. The floor plan is well-suited for optometry, ophthalmology, dental, dermatology, chiropractic, physical therapy, counseling, or general professional office use. Key property details: 2,244 SF on a single level. Built in 1950, well-maintained with a modern interior buildout. New roof installed in 2024. 15 on-site parking spaces (approximately 7 per 1,000 SF). Zoned for medical and professional office use. Single-tenant, owner-occupied. This property is located in the heart of North Syracuse, within the rapidly growing Central New York economic corridor. The area is positioned to benefit significantly from the Micron Technology semiconductor fabrication facility currently under construction in nearby Clay, NY, which is expected to bring substantial job growth and commercial demand to the surrounding communities. The building is available on its own at $400,000 or as part of a package with the established optometry practice (offered separately at $550,000). Seller financing may be available for qualified buyers.
Mechanical
Heating
Electric, Gas, Forced Air
Cooling
Central Air
Schools
District
North Syracuse
Tax & finance
Annual taxes
$10,374
Financing
Cash
MLS Attribution
Listing courtesy of Home With Us Realty Group, LLC. Listing agent: Jason Klink. Data last updated 5/19/2026. Information deemed reliable but not guaranteed; should be independently verified. © NYS Alliance of MLSs.
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